MedGenome is driven to enable clinicians to deliver the best outcomes to their patients. Our passion to deliver actionable insights to clinicians has resulted in the development of “Claria” - a suite of NGS (Next-Generation Sequencing) technology-based solutions for reproductive testing. Claria offers the most accurate Non-Invasive Prenatal Screening Test (NIPT), the Genetic Carrier Screening Test and the Preimplantation Genetic Screening/Diagnosis (PGS/PGD).
In addition to this Claria now offers not just advanced NGS based tests but also routine prenatal diagnostics and cytogenetic tests
The etiology of abortion is multifactorial and may involve endocrine, anatomic, immunological, infectious, environmental and genetic factors. About 60% of pregnancy losses are due to chromosomal abnormalaties. POC testing can detect whether the pregnancy had an abnormal chromosome number (aneuploidy) that might have caused a miscarriage. The information from POC testing can be helpful for patients and physicians to understand the cause of miscarriage and to develop a plan to support a future successful pregnancy.
POC testing was done earlier using Karyotyping and FISH, however these methods had several limitations such as requiring large number of cells and cell culture. Recently POC testing is being performed using molecular tests such as Chromosomal Microarray and Next Generation Sequencing.
Claria POC testing is done using the Affymetrix Optima Chromosomal Microarray (CMA).