Prosthetic Joint Panel

What is a Prosthetic Joint Panel Test?

Prosthetic joint panel test is a multiplex RT-PCR-based diagnostic assay designed for the rapid detection of bacterial and fungal infections in patients with joint replacements. It provides high sensitivity and specificity in identifying pathogens responsible for prosthetic joint infections (PJI), enabling early diagnosis and targeted antimicrobial therapy. Unlike traditional culture methods, this test delivers faster results, aiding in timely clinical decision-making to prevent implant failure, optimize patient management, and improve long-term prosthetic joint outcomes.

Pathogen Coverage in the Prosthetic Joint Panel

CategoryPathogens Detected
Bacterial PathogensStaphylococcus aureus, Staphylococcus epidermidis, Streptococcus agalactiae, Enterococcus faecalis, Pseudomonas aeruginosa.
Fungal Pathogen DetectionPan-fungal PCR (detects a broad range of fungal infections).
Bacterial Broad-Spectrum DetectionPan-bacteria PCR (identifies a wide range of bacterial infections).
Mycobacterial DetectionMtb/NTM PCR (detects Mycobacterium tuberculosis and nontuberculous mycobacteria).

Clinical Applications of the Prosthetic Joint Panel

  • Rapid and precise identification of infections.
  • Detects multiple pathogens, including difficult-to-culture bacteria.
  • Aids in early and targeted antimicrobial therapy.
  • Helps in distinguishing between infection and aseptic inflammation.

Specifications

  • Test Code: MG1889, MG1888, MG1799
  • Methodology: Multiplex RT-PCR
  • Turnaround Time: 1-2 working days
  • Specimen Type: Synovial fluid, tissue, aspirates.
  • Container: Sterile tube
  • Volume Requirement: As per laboratory guidelines.
  • Transportation Temperature: 2-8°C
  • Storage Conditions: -20°C if testing is delayed.

Diseases & Disorders Detected by the Prosthetic Joint Panel

Key Highlights of MedGenome's Prosthetic Joint Panel

Comprehensive Infection Detection

Rapidly identifies bacterial, fungal, and mycobacterial (Mtb/NTM) pathogens responsible for prosthetic joint infections (PJI) in a single test.

Essential for Early Diagnosis & Targeted Treatment

Helps detect infections before implant failure occurs, allowing clinicians to initiate appropriate antimicrobial therapy without delays.

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What is a Prosthetic Joint Panel Test?

Prosthetic joint panel test is a specialised test designed to detect infections in people with joint replacements, such as knee or hip implants. These infections can occur when bacteria or fungi grow around the artificial joint, causing pain, swelling, and difficulty moving. The test helps doctors quickly identify the cause of the infection so they can provide the right treatment, preventing further complications and protecting the joint.

How Does the Prosthetic Joint Panel Differ From Other Infection Tests?

FeatureProsthetic Joint Panel TestStandard Infection Tests
PurposeDetects infections in artificial joints.Identifies general infections anywhere in the body.
Pathogens DetectedBacteria and fungi that cause prosthetic joint infections.May not be specific to joint infections.
MethodologyMultiplex RT-PCR for fast and accurate results.Often relies on culture-based testing, which takes longer
Turnaround TimeFaster detection of infection-causing organisms.May take several days to identify pathogens.
Why Do You Need a Prosthetic Joint Panel Test?

If you have a joint replacement and are experiencing symptoms like pain, redness, swelling, or difficulty moving, this test can help determine if you have an infection.

  • Early detection prevents serious complications – If left untreated, infections in artificial joints can cause joint damage and implant failure.
  • Guides effective treatment – Identifies the exact bacteria or fungi causing the infection, allowing doctors to prescribe the right antibiotics or antifungal medication.
  • Faster and more accurate than traditional tests – Helps doctors start treatment sooner and reduces the need for unnecessary procedures.
How Does the Prosthetic Joint Panel Test Work?
How Is the Prosthetic Joint Panel Test Done?

The test is simple and requires a sample from the affected joint area.

  • Sample collection – A doctor collects a small amount of synovial fluid from the joint using a thin needle or takes a tissue sample during surgery.
  • Laboratory testing – The sample is analysed using multiplex RT-PCR to detect bacteria and fungi.
  • Results interpretation – The doctor reviews the test results to determine if an infection is present and what type of treatment is needed.
Who Should Consider a Prosthetic Joint Panel Test?
What Do Prosthetic Joint Panel Test Results Mean?
  • Positive for infection – This means bacteria or fungi have been detected, and your doctor will prescribe specific antibiotics or antifungal medication to treat the infection.
  • Negative for infection – No pathogens were found in the sample, but further testing may be needed if symptoms persist.
  • Multiple pathogens detected – Some infections involve more than one type of bacteria or fungi, requiring a combination of treatments.
What Infections Can a Prosthetic Joint Panel Detect?
Why Choose MedGenome for Your Prosthetic Joint Panel Test?

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