Comprehensive transplant panel works by analysing a patient’s sample to detect the presence of bacteria, viruses, and fungi that can cause infections after a transplant. It also checks for antimicrobial resistance (AMR) genes, which help doctors determine if certain infections are resistant to antibiotics. The test uses advanced molecular technology to quickly and accurately identify infections, allowing for early medical intervention to protect the transplanted organ and the overall health of the patient.
Comprehensive Transplant Panel
What is a Comprehensive Transplant Panel?
Comprehensive transplant panel is a molecular diagnostic test designed to detect bacterial, viral, and fungal infections, along with antimicrobial resistance (AMR) genes, in transplant recipients. Utilising multiplex RT-PCR technology, this test rapidly identifies opportunistic pathogens such as CMV, EBV, Candida species, and multidrug-resistant bacteria, which pose a significant risk to immunosuppressed patients. By enabling early infection detection and targeted antimicrobial therapy, the comprehensive transplant panel enhances post-transplant monitoring, reduces complications, and improves long-term graft survival.
Pathogen Coverage in the Comprehensive Transplant Panel
| Category | Pathogens Detected | |
|---|---|---|
| Gram-Positive Bacteria | Staphylococcus spp, Staphylococcus aureus, Streptococcus spp, Streptococcus pneumoniae, Enterococcus faecium, Enterococcus faecalis, Listeria monocytogenes. | |
| Gram-Negative Bacteria | Neisseria meningitidis, Haemophilus influenzae, Pseudomonas spp, Pseudomonas aeruginosa, Klebsiella pneumoniae, Klebsiella oxytoca, Acinetobacter baumannii, Stenotrophomonas maltophilia, Escherichia coli, Enterobacteriaceae. | |
| Antimicrobial Resistance (AMR) Genes | VanA (Vancomycin resistance), VanB (Vancomycin resistance), OXA-48 (Carbapenem resistance), KPC (Carbapenem resistance), NDM (Carbapenem resistance), VIM (Carbapenem resistance), IMP (Carbapenem resistance), mecA/mecC (Methicillin resistance). | |
| Fungi | Candida krusei, Candida glabrata, Candida albicans, Candida parapsilosis, Candida tropicalis. | |
| Viruses | Enterovirus; Epstein-Barr virus (EBV); Herpes Simplex virus 1 (HSV-1); Herpes Simplex virus 2 (HSV-2); Human Adenovirus ;Human Cytomegalovirus (CMV) Human Herpesvirus 6 (HH6); Human Herpesvirus 7 (HH7); Human Parechovirus; Human Parvovirus B-19; Varicella Zoster virus (VZV); JC virus; BK virus. |
When is the Comprehensive Transplant Panel Recommended?
- Post-Transplant Monitoring – Detects early infections and antimicrobial resistance genes, ensuring timely intervention.
- Essential for Solid Organ & Stem Cell Transplants – Recommended for kidney, liver, heart, lung, and hematopoietic stem cell transplant patients.
- Improves Long-Term Transplant Success – Helps reduce complications, enhance graft survival, and prevent life-threatening infections.
Specifications
- Test Code: MGM3206
- Methodology: Multiplex RT-PCR
- Turnaround Time: 2 working days
- Specimen Type: Whole Blood
- Container : EDTA Tube
- Transportation Temperature: 2-8°C
- Volume Requirement: 3ml
- Storage Conditions: Samples should be transported within 24 hours of collection.
Diseases & Disorders Detected by the Comprehensive Transplant Panel Test
Applicable for Diseases
End-stage organ failure (kidney, liver, heart, lung)
Hematological malignancies requiring stem cell transplantation
Congenital immunodeficiencies
Applicable for Disorders
Graft-versus-host disease (GVHD)
Transplant rejection
Post-transplant infections
Key Highlights of MedGenome's Comprehensive Transplant Panel
Comprehensive Infection Screening
Detects bacterial, viral, and fungal infections, along with antimicrobial resistance (AMR) genes, ensuring early identification of post-transplant complications.
Fast Turnaround Time for Timely Intervention
Provides results within 2 working days, allowing for quick clinical decision-making and personalised patient care.
Trusted by 24,000+ Clinicians
MedGenome is trusted and recommended by 24,000+ clinicians and 8,000+ hospitals across India and South Asia.
Get Genetic Counselling by Our Experts
Connect with Our Experts
MedGenome Patient Stories
MedGenome in the News
Please share your details to get
in touch with our experts.
