Gastrointestinal Pathogen Panel

Precise diagnosis for gastrointestinal infections

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What is the Gastrointestinal Pathogen Panel?

Gastrointestinal Pathogen Multiplex PCR Panel is a CE-IVD real-time, multiplex PCR-based test. It detects and differentiates 15 bacteria, 3 parasites, and 5 viruses that cause gastroenteritis. This Gastrointestinal Pathogen Panel Test allows the simultaneous identification of multiple pathogens in a single stool sample.

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List of Pathogens Covered

Category	Details
Bacteria	Campylobacter spp., Salmonella spp., Yersinia enterocolitica, Clostridium difficile toxin A, Clostridium difficile toxin B, Shiga toxin producing E. coli (STEC), stx1/ stx2, Enteropathogenic E. coli (EPEC), eae Enterotoxigenic E. coli (ETEC), elt/est, Shigella/ enteroinvasive E. coli (EIEC), ipaH.
Parasites	Entamoeba histolytica, Giardia lamblia, Cryptosporidium spp., Dientamoeba fragilis.
Virus	Norovirus (GI/GII/GIV), Rotavirus (A), Adenovirus (40/41), Astrovirus, Sapovirus (GI/ GII/GIV/GV).

When to Recommend the Gl Pathogen Panel Test

Diarrhoea with Complications: Presence of fever, severe abdominal cramps, or signs of sepsis.
Moderate to Severe Symptoms: Cases requiring urgent identification of the underlying cause.
High Risk of Disease Transmission: During outbreaks or in individuals who may spread the infection.
Dysentery Cases: Presentation with bloody diarrhoea for pathogen identification.
Persistent Symptoms: Diarrhoea lasting more than seven days without resolution.
Immunocompromised Individuals: Patients with weakened immunity experiencing diarrhoea.

Specification

Test Codes: MGM1728
Sample Type: Stool (pea-sized or 2ml of unformed stool) collected in a sterile wide-mouth container.
Precautions: Avoid contamination with urine or water.
Storage Guidelines: If not processed immediately, store at 4°C and transport at the same temperature. For delays exceeding 48 hours, freeze the sample at or below -20°C (preferably -70°C) and transport at the same temperature.
Methodology: Multiplex Real-Time PCR
Turnaround Time (TAT): 2 working days

Targeted Pathogens in MedGenome’s GI Panel

Bacterial Targets

Yersinia enterocolitica, Plesiomonas shigelloides, Vibrio vulnificus, Cyclospora cayetanensis, Salmonella spp., Campylobacter spp., Vibrio parahaemolyticus, Vibrio cholerae, Shiga toxin-producing Ecoli (STEC), Enteropathogenic Ecoli (EPEC), Enterotoxigenic E.coli (ETEC), Shigella/Enteroinvasive E.coli (EIEC), Entroaggregative E.coli (EAEC), Clostridium difficile toxin A, Clostridium difficile toxin B, Clostridium difficile Binary toxin A/B.

Viral and Parasitic Targets

Human Sapovirus (GI/GII/GIV/GV), Human Adenovirus Type F, Human Astrovirus, Human Norovirus (GI/GII), Human Rotavirus (A), Giardia lamblia, Entamoeba histolytica, Cryptosporidium spp.

Key Highlights of MedGenome Labs GI Panel TEST

Comprehensive Pathogen Detection

Identifies 23 pathogens in a single tube, unlike assays requiring separate panels for bacteria, viruses, and parasites.

Flexible Sample Handling

Works with fresh or frozen stool specimens without pre-treatment or transport media.

Extensive Validation

Thoroughly validated for potentially cross-reactive pathogens with guaranteed 100% sensitivity and specificity.

Co-Infection Identification

Precisely detects co-infections, which are common in gastrointestinal diseases.

What is Gastrointestinal Pathogen Infection?

A Gastrointestinal (GI) Pathogen Infection occurs when harmful pathogens, such as bacteria, viruses, or parasites, infect the digestive tract, leading to symptoms like diarrhea, vomiting, abdominal pain, and fever.

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Importance of Detecting GI Infections

Reason	Importance
Rapid diagnosis for early treatment	Enables timely and appropriate treatment, reducing complications.
Prevention of severe outcomes	Prevents serious issues like dehydration, sepsis, or chronic illness.
Outbreak control	Helps contain infections in hospitals, communities, or during foodborne outbreaks.
Antibiotic stewardship	Avoids misuse of antibiotics, helping combat antimicrobial resistance.
Differentiation of pathogens	Ensures correct treatment by distinguishing between pathogens with similar symptoms.

What is the Gastrointestinal Pathogen Panel?

The Gastrointestinal Pathogen Panel is a highly advanced test designed to identify a wide range of bacteria, viruses, and parasites that cause stomach and intestinal infections, commonly known as gastroenteritis. Unlike conventional GI pathogen panels, such as stool culture, microscopy for ova and parasites, ELISA, and rapid lateral flow tests, which can only detect one or a few pathogens at a time, this advanced GI panel test can detect 19 different pathogens in one go.

The test includes 10 bacteria, 4 parasites, and 5 viruses, making it a thorough and quick way to figure out what is causing your infection. This comprehensive approach ensures you get a precise diagnosis swiftly, enabling timely and effective treatment.

Who Should Consider Getting the Gastrointestinal Pathogen Panel Test?

Why Choose MedGenome Labs for the Gastrointestinal Pathogen Panel?

MedGenome Labs is a trusted name in diagnostic testing, offering cutting-edge solutions for infectious diseases. Here’s why MedGenome Labs stands out for the GI Pathogen Panel Test:

Comprehensive Testing: Unlike other assays, MedGenome Labs’s Gastrointestinal Panel Tests for all 23 pathogens in a single test to ensure a complete and efficient diagnostic process.
Quick Results: Our GI panel test results are available within two working days after the lab receives your sample.
Validated Accuracy: Extensive validation ensures 100% sensitivity and specificity, accurately detecting all targeted pathogens without false positives or negatives.
Ease of Sample Collection: The gastrointestinal panel test can be conducted using fresh or frozen stool samples, with minimal preparation needed.
Detection of Co-Infections: Identifies co-infections, which are common in gastrointestinal diseases but often missed by conventional tests.

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