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Condition



Test Name

Somatic Cancer Mutation Panel (Hot Spots; SNVs and small INDELs)

Inclusive Genes



Provide histopathological report of patient Inclusive genes: ABL1, AKT1, ALK, APC, ATM, BRAF (inclusive of v600E), CDH1, CDKN2A, CSF1R, CTNNB1, DDR2, DNMT3A, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, FOXL2, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MAP2K1/MEK1, MET, MLH1, MPL, MSH6, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, SRC, STK11, TP53, TSC1, VHL Except for TP53 only specific hotspots are covered in the aforementioned genes, that is, those which are therapeutically relevent. Specific exonic coverage will be provided on individual reports

Specimen Type

FFPE blocks

Container

Transportation Temperature

20-25⁰C

Volume

Minimum 10% (as assessed by the pathologist) of tumor tissue should be available

Methodology

Next Generation Sequencing

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Genetic Counselling

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