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Condition



Test Name

HLA-B* 1502 for carbamazepine toxicity

Inclusive Genes



HLA-B* locus is evaluated to identify the HLA-B 1502 variation which is linked to Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) complications in patients receiving Carbamazepine

Specimen Type

Peripheral blood; purified genomic DNA; buccal swabs (4) for patients on chemotherapy or anemic patients with a WBC count <1000/uL

Container

Transportation Temperature

20-25⁰C

Volume

Minimum 3ml of peripheral blood; minimum 1 microgram of DNA (concentration of 50-100ng/microliters); 4 buccal swabs

Methodology

Next Generation Sequencing

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