A 14-year-old female had heart attack/MI and underwent anterior wall Myocardial
Infarction on 06.10.2020. She is currently on antiplatelet, statins and heparin
medication. She was suggested to undergo Coronary Artery Disease -Polygenic Risk
Score Test to find out whether she was at high risk of getting Coronary Artery Disease.
No history of heart disease, hypertension and hypercholesterolemia in the family.
Genetic testing at MedGenome
Coronary Artery Disease -Polygenic Risk Score Testing was done at MedGenome.
The person has a PRS of 1.43 (blue dotted line), which indicates a population high
polygenic risk, with an odds ratio of 2.43 relative to MedGenome’s cohort.
The Coronary Artery Disease – Polygenic Risk Score (CAD-PRS) for the person was
found to be 1.43. This score has been profiled as a high risk as observed in
MedGenome’s study cohort of South Asian ancestry. The person carries a high
polygenic risk of getting CAD, with an OR of 2.43, based on MedGenome’s study
cohort. Thus the CAD PRS test can accurately predict the risk of CAD in very young