MedGenome Micra Webinar on SPIT SEQ
MedGenome cordially invites you to a webinar on
SPIT SEQ- Whole Genome Sequencing of Mtb for diagnosis and drug resistance profiling in Tuberculosis
Date & Time:
19th December, 8:00 pm IST
- Tuberculosis (TB) is a communicable disease that is a major cause of ill health, one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent.
- TB is caused by the bacillus Mycobacterium tuberculosis, which is spread when people who are sick with TB expel bacteria into the air; for example, by coughing.
- Globally, 7.1 million people with TB were reported to have been newly diagnosed and notified in 2019, of which India accounts for 2.64 million TB cases.
- Geographically, in 2019, Eight countries accounted for two thirds of the global total: Of Which with 26% India ranking first among them. Followed by Indonesia (8.5%), China (8.4%), the Philippines (6.0%), Pakistan (5.7%), Nigeria (4.4%), Bangladesh (3.6%) and South Africa (3.6%).
- Next-generation sequencing (NGS) has a great potential for the rapid diagnosis of drug-resistant tuberculosis (DR-TB) in diverse clinical reference laboratory settings worldwide.
- The NGS approach overcomes many of the significant challenges associated with conventional phenotypic testing as well as the limitations of other less comprehensive molecular tests by providing rapid, detailed sequence information for multiple gene regions or whole genomes of interest.
- However, the uptake of these technologies for DR-TB diagnosis has been hindered by concerns regarding costs, integration into existing laboratory workflows, technical training and skill requirements for utilization of the technology, and the need for expert guidance regarding the management and clinical interpretation of sequencing data.
- A direct sputum-based whole genome sequencing of Mtb test helps clinicians identify the presence of mutations that render the Mycobacterium resistant.
Dr. Anil Kumar
Clinical Professor & HOD of Microbiology at Amrita Institute of Medical Sciences, Kerala.
Dr. Lakshmi Soundararajan
Senior Scientist, Infectious Diseases, MedGenome Labs Ltd.